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Principles and practice of Clinical parasitology - Gillespie S.

Gillespie S. Principles and practice of Clinical parasitology - Wiley publishing , 2001. - 675 p.
ISBN 0-471-97729-2
Download (direct link): principlesandpracticeofclin2001.pdf
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DNA Vaccines
DNA immunisation involves the direct introduction of a plasmid DNA encoding a target antigen, which is then expressed within cells of the host and can stimulate an immune response. This approach will allow a combination of many DNAs, each encoding different antigens, thereby broadening the immune response. Animal studies using genes encoding P. yoelii sporozoite proteins have so far been encouraging (Doolan et al., 1998).
We acknowledge the help of Heather Saunders and Virginia Champion de Crespigny in preparing the manuscript, Joe Manitta and Stephen Rogerson for slide microscopy and Kevin Kain for reviewing the text.
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