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biopharmaceuticals biochemistry and biotecnology - Walsh G.

Walsh G. biopharmaceuticals biochemistry and biotecnology - John Wiley & Sons, 2003. - 572 p.
ISBN 0-470-84327-6
Download (direct link): biochemistryandbiotechnology2003.pdf
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Rules Governing Medicinal Products in the European Union 85
S-oligos 492-3 Sabin vaccine 438, 439 Saccharomyces cerevisiae 116, 117 safety 5
Saizen 329, 501
salicin 33, 34
salicylic acid 33, 34
Salk vaccine 438, 439
salmon calcitonin 347
Sanofi-Synthelabo 507
saponins 459
sargramostim 261
Schering AG 209, 502
Schering Plough 11, 209, 502, 503, 511
Schwann cells 295
Schwartz Pharma AG 329, 501
scopolamine 28-9
scorpion venom antisera 406, 409
screening 53
SDS-PAGE 164, 165
SE-HPLC 168
secondary structure analysis 173 seminal fluid, transgenic animals 122 sensitivity gene 486, 487 sensory neurons 295 septic shock cytokines 196 monoclonal antibodies 434 tumour necrosis factor 251 sequence homology 47 Seragen inc 507 Serono Laboratories 329, 501 Serostim 329, 501 Sertoli cells 334, 338 serum albumin 150-1 serum sickness 404
severe combined immunodeficiency (SCID) 226, 483-4
INDEX 549
sex hormones 13, 14-19
Shc 290
sheep
defleecing 287 milk 118 Shope fibroma virus 196 short stature 283, 327, 328-30 shotgun approach 490-1 sickle cell anaemia 353, 483 Sicor 10
silkworms 123, 124, 219 silver-binding method 163, 164 Simulect 416, 435, 505 sindbis virus 473
single nucleotide polymorphisms (SNPs) 52 single peak insulins 310 sissomicin 38
site-directed mutagenesis 5, 7 size exclusion HPLC 168 Smad proteins 293 smallpox 446
SmithKline Beecham 441, 442, 503, 504 snake venom 5 antisera 406, 408-9 SNT-1 290
SOCS/Jab/Cis family 202 sodium caprylate 356
sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) 164, 165 sodium hydroxide 104 soft tissue sarcoma 252 somatomedins 279 somatorelin 324 somatostatin 325 somatotrophin 9, 324 sorbitol 152 Sorin 416, 506 Span 456 specifications 110 sperm cell production 334 spider antivenins 406, 408-9 split synthesis 56-7, 60 Spodoptera frugiperda 123 Src 290
stabilizing agents 143, 150-2
standard operating procedures (SOPs) 110
stanozolol 15, 16
staphylokinase 381, 386-8
starvation 283
STATs 200
steam 178
stem cells 255, 484, 486 sterility testing 180 steroid (sex) hormones 13, 14-19 stilboesterol 15, 17, 18 stomach acid 66
stomach ulcers 29 streptokinase 381, 385 streptomycin 35, 38 Streptozon 7 stress response 330 stroke 372, 381 structural genomics 50 structure-based drug design 54 Stryker 507 Stuart factor 359 study population 75 subfertility 339, 341-2, 344 subunit vaccines 441-4, 451 succinylation 390 sufficiency of disclosure 62 sulpha drugs 4, 6, 7 sulphanilamide 6, 7 superovulation 339, 344-5 superoxide dismutase 397 superoxide radical 397 surfactant lungs 67, 260 stabilizers 152 SV40 427
swine fever vaccine 124 Synagis 416, 506 synapse 295
Syntex adjuvant formulation-1 (SAF-1) 458 synthetic immune libraries 414 syphilis 3
T-bag synthesis 56 T cell growth factor 225 T cytotoxic cells 191 T helper cells 191 T helper type 1 lymphocytes 244 T lymphocytes 191, 417 T suppressor cells 191 tamoxifen 16, 18 targeted screening 53 tat 487
taxol 4, 28, 31, 32-3 99mTC (technetium) 420-1 Tecnemab-K-1 421-2 Tecnemab KI 416, 506 Tenecteplase 381, 385, 500 teratogenicity 71 terpenoids 30-3 tertiary structure analysis 173 testosterone 14, 15, 16, 335, 336, 337 testosterone-oestradiol binding globulin (TEBG) 14
tetanus
antitoxin 406 immunoglobulin 406, 408 vaccine 438, 440
550 INDEX
tetracyclines 37
tetrahydrofolic acid 7
thalassemias 483
theca cells 334, 335, 336
theophylline 28, 31, 32
thiamphenicol 39
thioredoxin 114
Thompson, Leonard 305
3D searching with receptor-based queries 512
threonyl-MDP 457, 458
thrombin 361, 362, 365
thrombocytes 273
thrombocythaemia 273
thrombocytopenia 240, 273-4
thromboembolic event 273
thrombolytic agents 11, 380-9
thrombomodulin 380
thromboplastin 359
thrombopoietin 273-5, 278
thrombus 372
Thyrogen 347, 501
thyroid cancer 346
thyroid-stimulating hormone (TSH) 345, 346-7 thyrotrophin 346 thyrotrophin-a 347
thyrotrophin releasing hormone (TRH) 346 thyroxine 346
thyroxine binding globulin 356 tick anticoagulant peptide 377 tick-borne encephalitis immunoglobulin 406 tissue-based agents 4 tissue factor 359
tissue plasminogen activator (tPA) 113, 118, 136, 381-5, 500 TKT Europe 395, 507 TNF-R55 249 TNF-R75 249 TNFR1 249 TNFR2 249 TNKase 381, 500 tobacco 122 tobramycin 38 toxicity studies 71
toxins, delivery to tumour sites 422-4 toxoids 440
traditional pharmaceuticals 12-39 transcortin 356 transcytosis 68 transdermal delivery 68-9 transferrin 356
transforming growth factors (TGF-aand TGF-b) 278, 290, 292-3 transgenic animals 118-22 patenting 65 transgenic plants 122-3 transmucosal delivery 68-9
transplantation 231, 263, 272-3, 434-5 transthyretin 356 b-trefoil cytokines 192 trehalose dimycolate 456-7 Treponema pallidum 352 Triacelluvax 442, 504 triidothyronine 346 Tritanrix-HB 441, 442, 503 Trks (Trk A, B, C) 296-7 trophoblastin 218-19 true endocrine hormone 303 Trypanosoma cruzi 352 trypsin 13, 170, 398 tuberculosis 230 tumour escape 229
immunology 415, 417-28 see also cancer tumour-infiltrating lymphocytes (TILs) 230,
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