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Analitical techniques in combinatorial chemistry - Swarth M.E.

Swarth M.E. Analitical techniques in combinatorial chemistry - Marcel Dekker, 2000. - 311 p.
ISBN 0-8247-1939-5
Download (direct link): analyticaltechniquesincombinatorialchemistry2000.pdf
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204
Spectroscopy (see also Nuclear magnetic resonance) attenuated total reflectance, 67 Cassegrain objectives, 70 fluorescence, 15 infrared, 65-70 transmission, and polystyrene resin, 66 transmission, and potassium bromide disks, 66 transmission, using Tentagel beads, 66 internal reflection, 67-70 and KBr, 69 and selenide, 68 and silicon, 68 and solid polymer substrates,
68
and Split Pea accessory,
69
and Tentagel, 69 micro-, 68, 70
Index
[Spectroscopy] and microphones, 71 photo-acoustic, 70-71 depth profiling, 71 interferometers, 71 step-scan, 71 raman, 65, 73-74
and Fourier transform, 74 and Tentagel beads, 74 and Tentagel, 71 Synthesis biopolymer, 6 peptide, 6 design process, 177 module, 182 determistic split-and-pool, 16 functionalized polymers, 7 high-throughput organic, 174 automated, 205-206 and MS, 35 and NMR, 101 organic, 4
organic solution phase, 4 parallel, 2, 8, 174 automated, 17-20 ChemSheet, 19
using grafted polyethylene pins,
19
photolithography, 19
[Synthesis]
reaction block, 18 reactors, 18 workstations, 18 product analysis, 184 product registration, 185 reaction workbook, 182 and robotics, 183 serial, 2 reagents, solid supported, 5 solid phase, 5, 7, 29 automation, 6 cleavage, 6 nonoligomeric, 8 resin, 6, 9
split-and-pool, 9-13, 15-16 solution phase, 5 statistical split and pool, 16
Tagging
chemical, 178
by radiofrequency encoding,
178
Tracking reagents, 178
Validation, 179
Vancomycin, 44, 156, 158
Xanthene derivatives, 160
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