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Solid-phase organik syntheses - Burdges K.

Burdges K. Solid-phase organik syntheses - John Wiley & Sons, 2000. - 283 p.
ISBN 0-471-22824-9
Download (direct link): phaseorganicsynthesis2000.pdf
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56. McQuaid, L. A.; Smith, E. C. R.; South, Ê. K.; Mitch, Ñ. H.; Schoepp, D. D.; True, R. A.; Calligaro, D. O.; O’Malley, P. J.; Lodge, D.; Ornstein, P. L. Synthesis and Excitatory Amino Acid Pharmacology of a Series of Hetero-cyclic-Fused Quinoxalinones and Quinazolinones, J. Med. Chem. 1992, 35, 3319.
57. Mule, A.; Pirisino, G.; Manca, P.; Satta, ̀.; Peana, A.; Savelli, F. Tertiary-Aminoalkyl Derivatives of Quinoxalinones and of Aza- and Diazaquinoxali-nones With Analgesic Activity, Farmaco, Ed. Sci. 1988, 43, 613.
58. Sarges, R.; Lyga, J. W. Synthesis and Aldose Reductase Inhibitory Activity of N-l,N-4-Disubstituted 3,4-Dihydro-2(lH)-quinoxalinone Derivatives, J. Heterocycl. Chem. 1988, 25, 1475.
59. For recent reviews on specific drugs containing the benzimidazole nucleus, see for example: Telmisartan. BIBR-277, Merlos, ̀.; Casas, A.; Castaner, J. Drugs Future 1997, 22, 1112. Mibefradil Hydrochloride. Ro-40-5967. Posicor® Cerate 50, Casas, A.; Graul, A.; Castaner, J. Drugs Future 1997,
22, 1091. 1263W94. Antiviral, Graul, A.; Tracy, ̀.; Castaner, J. Drugs Future 1997,22,707. Omeprazole, an Antiulcer Drug that Inhibits the Proton Pump, Boza, A.; Sablon, ̀.; Castillo, J. A. Rev. CENIC, Cienc. Biol. 1996,
27, 50. Mebendazole and Related Antihelmintics, Van den Bossche, H.; Rochette, F.; Hoerig, C. Adv. Pharmacol. Chemother. 1982, 79, 67.
60. For general reviews on biological activities of benzimidazoles, see for example: Similarities and Differences in the Properties of Substituted Benzimidazoles: A Comparison Between Pantoprazole and Related Compounds, Kromer, W. Digestion, 1995, 56, 443. The Use of Benzimidazole Derivatives in Medicinal Chemistry, Soula, C.; Luu-Duc, C. Lyon Pharm. 1986,37,297. The Benzimidazole Antihelmintics—Chemistry and Biological Activity, Sharma, S.; Abuzar, S. Prog. Drug Res. 1983, 27, 85. The Development of Nonpeptide Angiotensin II Receptor Antagonists. A Success Story, Hoeltje, H. D.; lessen, G.; Hoeltje, M. Pharmazie 1997, 52, 83. DNA Sequence Recognition Altered Bis-Benzimidazole Minor-Groove Binders, Lown, W. Adv. DNA Sequence Specific Agents 1998, 3, 67.
61. Phillips, G. B.; Wei, G. P. Solid Phase Synthesis of Benzimidazoles, Tetrahedron Lett. 1996, 37, 4887.
REFERENCES 117
62. Kugishima, H.; Horie, ̉.; Imafuku, K. Synthesis of 3-[[(2-Benzimida-zolyl)thio]methyl]-1 -methyl-1,8-dihydrocycloheptapyrazol-8-ones, J. Het-erocycl. Chem. 1994, 31, 1557.
63. Cereda, E.; Turconi, ̀.; Ezhaya, A.; Bellora, E.; Brambilla, A.; Pagani, F.; Donetti, A. Antisecretory and Antiulcer Activities of Some New 2-(2-Pyridylmethylsulfinyl)-benzimidazoles. Eur. J. Med. Chem. 1987, 22, 527.
64. Saluja, S.; Zou, R.; Drach, J. C.; Townsend, L. B. Structure-Activity Relationships among 2-Substituted 5,6-Dichloro-, 4,6-Dichloro- and 4,5-Di-chloro-1-[(2-hydroxyethoxy)methyl]- and -1-[(1,3-dihydroxy-2-propoxy)methyl]benzimidazoles, J. Med. Chem. 1996, 39, 881.
65. Ellingboe, J. W.; Spinelli, W.; Winkley, M. W.; Nguyen, ̉. ̉.; Parsons, R. W.; Moubarak, I. F.; Kitzen, J. ̀.; Von Engen, D.; Bagli, J. F. Class III Antiarrhythmic Activity of Novel Substituted 4-[(Methylsulfonyl)amino]-benzamides and Sulfonamides, J. Med. Chem. 1992, 35, 705.
66. Holmes, D. S.; Bethell, R. C.; Cammack, N.; Clemens, I. R.; Kitchin, J.; McMeekin, P.; Mo, C. L.; Orr, D. C.; Patel, B. et al. Synthesis and Structure-Activity Relationships of a Series of Penicillin-derived HIV Proteinase Inhibitors Containing a Stereochemically Unique Peptide Isostere, J. Med. Chem. 1993, 36, 3129.
67. Billich, A.; Aziz, A.; Lehr, P.; Charpiot, B.; Gstach, H.; Scholz, D. Kinetic and Binding Studies on [ 125I]SDZ-283471, A Radiolabeled Inhibitor of HIV-1 Proteinase, J. Enzyme Inhib. 1993, 7, 213.
68. Schwarz, ̀. K.; Gallop, M. A., unpublished results.
69. Studies on the Chemistry of Thienoannulated 0,N- and S,N-Containing Heterocycles. 1. Nucleophilic Substitution Reactions on Chlorinated Thio-phene Derivatives as a Basis for the Synthesis of Thienoannulated 0,N- and
S,N-Heterocycles, Puschmann, I.; Erker, T. Heterocycles 1993,36,1323. See also: Studies on the Chemistry of Thienoanellated 0,N- and S,N-Containing Heterocycles. II. Synthesis on Thieno-Dilthiazem Analogs, Puschmann, I.; Erker, T. Heterocycles 1995, 41, 709.
Solid-Phase Organic Synthesis. Edited by Kevin Burgess Copyright © 2000 John Wiley & Sons, Inc. ISBNs: 0-471-31825-6 (Hardback); 0-471-22824-9 (Electronic)
CHAPTER 4
SOLID-PHASE SYNTHESIS OF SEQUENCE-SPECIFIC PHENYLACETYLENE OLIGOMERS
(iv) repeat
JEFFREY S. MOORE, DAVID J. HILL, and MATTHEW J. MIO The University of Illinois at Urbana-Champaign
4.1. INTRODUCTION
Solid-phase organic synthesis (SPOS) is an established technique for generation of peptides,1,2 nucleotides,3 and more recently, carbohydrates (oligosaccharides).4-5 Supported syntheses of nonbiological oligomers6-16 and other small molecules17-21 have also been reported, reflecting the method’s
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